NCA30946 Micro-array based genotyping, DecodeMe, IGMM

Concepts

• nca30946 micro-array
• edinburgh
• laboratory services
• micro-array
• genotyping
• decodeme
• igmm
• ukri

Location

Description

Micro-array based genotyping for our UKRI-funded BLOOM study

Total Quantity or Scope

Micro-array based genotyping

Award Detail

Award Criteria

CPV Codes

• 71900000 - Laboratory services

Legal Justification

To ensure its success, it is essential that the DecodeME project undertakes genotyping of the 20,000 ME/CFS cohort using the Affymetrix Axiom® array, and this is only possible via ThermoFisher who is Affymetrix’s parent company. The reason is that the project is only well-powered if – for its UK gender-, age- and ancestry-matched control samples – it takes advantage of the 500,000-strong UK Biobank cohort. Specifically, the project needs the genotypes of its cases (people with ME/CFS) to have been acquired using the exact same array as the controls (UK Biobank) and these were acquired using exactly this technology, i.e. the Affymetrix Axiom® array. Otherwise – if a different array is used – there is potential that technical errors would introduce spurious findings which might lead us to arrive at false scientific conclusions.

Other Information

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