A system for non-invasive preclinical ultrasound imaging

Concepts

• reading
• instruments
• single system
• purchase of a system
• following preclinical models
• m-mode images
• analysis of the images
• imaging of pig hearts
• non-invasive preclinical ultrasound
• above preclinical models

Location

South East England: University of Reading Whiteknights Campus Reading

Description

For the purchase of a system for non-invasive preclinical ultrasound imaging. A single system is to be purchased that will permit visualisation of all of the following preclinical models: • Mouse embryos and zebrafish at resolutions down to 30 µm using an ultra-high frequency transducer (up to 71 MHz). • Mouse hearts and the vasculature in genetic and drug-induced models of disease at 30 µm resolution using a transducer of 30-40 MHz with a frame rate capable of imaging heart rates of up to 750 beats per minute. ECG-gating is also required for 3D reconstruction of the heart. • Rat hearts and the vasculature in genetic and drug-induced models of disease (as detailed above for mice) using a transducer of ~29 MHz. • Mouse or rat brains (requiring a lower frequency transducer of ~22 MHz). Additional capability is required for upgrading for imaging of pig hearts and the vasculature (requires low frequency transducers of 4-10 MHz) and for photoacoustic imaging. The system must have the following provision: • Integrated physiology traces for small animals, including display of ECG, respiration waveform, and body temperature. • Capability for capturing B-mode and M-mode images, and for analysis of the images to provide data on cardiac and vascular function and dimensions in the above preclinical models (including strain and speckle-tracking). • Capability for Power Doppler, Pulsed-Wave Doppler, Pulsed-Wave tissue Doppler and colour Doppler for assessment of blood flow. • Capability for contrast imaging. The University has published this VEAT notice and intends to award a contract to FUJIFILM Visualsonics Inc. following the expiry of 10 full calendar days after the expiry of this notice.

Award Detail

CPV Codes

• 38400000 - Instruments for checking physical characteristics
• 38000000 - Laboratory, optical and precision equipments (excl. glasses)

Legal Justification

Absence for technical reasons due to the patents and requirement to have the key features of the instrument which are 1) the ability for ultrasound imaging across the spectrum of preclinical models using low to high frequency transducers (4 - 71 MHz), 2) capability for high resolution (30 µm) cardiovascular and cardiac imaging and analysis in small animal preclinical models with high heart rates, 3) capability for brain imaging in mice and rats, 4) capability for upgrading for photoacoustic imaging and 5) fully integrated software for instrument operation and data analysis

Other Information

** PREVIEW NOTICE, please check Find a Tender for full details. **