Dianthus Nano System

Concepts

• durham
• machines and apparatus
• nanotemper technologies gmbh
• dianthus nano system
• veat notice
• university
• testing and measuring
• ion and molecular microscopes
• latest innovation
• date of publication of this notice

Location

Durham

Description

The University has a requirement to purchase an instrument that features the latest innovation for characterising biomolecular binding affinities. The University has published this VEAT notice and intends to award a contract to NanoTemper Technologies GmbH following the expiry of 10 days from the date of publication of this notice.

Award Detail

CPV Codes

• 38540000 - Machines and apparatus for testing and measuring
• 38512000 - Ion and molecular microscopes
• 38544000 - Drug detection apparatus

Legal Justification

Specific features of the system include the • Measurements are performed in solution (i.e. no immobilisation is required) • Capability to quantify interactions in complex solutions (crude extract, serum) • Means to determine binding constant over a wide range (5 nM - high millimolar) as well as stoichiometry and thermodynamic parameters • Power to work at low nanomolar concentrations • Advantage of small sample volumes (20 microliter) coupled with the capacity to run samples in high-throughput mode using standard 384 well-plate • Used detection modalities based on two techniques: Spectral shift detection and Temperature-Related Intensity Change (TRIC) • Microfluidics-free • Mass independent measurement i.e., the measurable molecular weight range is from 101-107 Da • Measure up to 384 datapoints per run • Advantage of small sample volumes (20 microliter) coupled with the capacity to run samples in high-throughput mode using standard SBS 384 well-plate format

Other Information

** PREVIEW NOTICE, please check Find a Tender for full details. **