Dynamic Light Scattering machine

Concepts

• woking
• dynamic light scattering machine
• light
• machine
• scattering
• vivo immunogenicity studies
• such studies
• rna vaccines
• livestock cvim
• formulated mrna vaccine candidates

Location

Description

As a first step towards evaluating the use of RNA vaccines for livestock, the Centre for Veterinary Vaccine Innovation and Manufacturing (CVIM) collaborated to carry out a proof-of-principle study. The success of this work has led to the continued evaluation by CVIM of RNA-based vaccines for livestock. To enable this, CVIM is developing an in-house RNA platform. To facilitate the continued evaluation of RNA-based vaccines for livestock CVIM needs to develop the capacity to produce formulated mRNA vaccine candidates at a suitable scale to carry out in vivo immunogenicity studies. This platform requires stringent in-process quality control (QC). A dynamic light scattering (DLS) machine is required to check the integrity of encapsidated RNA particles prior to its use in such studies.

Award Detail

CPV Codes

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Other Information

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