250262 - Contract for Supply, Delivery, Installation & Commissioning of a Surface Plasmon Resonance (SPR) System

Concepts

• belfast
• detection and analysis apparatus
• system
• installation
• surface
• plasmon
• spr
• resonance
• analysis apparatus
• protein purification

Location

Description

The Future Medicines Institute (FMI) requires a Surface Plasmon Resonance (SPR) system with advanced capabilities for real-time, label-free analysis of biomolecular interactions. (Maximum budget available for Equipment inclusive of 3 years extended warranty & annual preventative maintenance is is £330,000). The primary objective of procuring an SPR device is to enhance FMI’s capacity to characterise binding kinetics, affinity, and specificity of biomolecular interactions, thereby strengthening its protein science and drug discovery workflows. The proposed system must: • Provide precise kinetic and affinity measurements for a wide range of biomolecular interactions, including protein–protein, protein–antibody, and protein–small molecule binding. • Deliver high sensitivity and reproducibility to ensure reliable and quantitative data across experiments. • Support automation and high-throughput analysis, enabling efficient screening of large sample sets. • Include robust data analysis software for comprehensive kinetic modelling and data interpretation. • Offer versatile assay configurations, supporting various experimental formats and immobilisation chemistries. • Integrate seamlessly with upstream and downstream workflows, including protein purification and structural analysis. The procurement of a high-performance SPR system directly supports FMI’s broader goals of: • Accelerating drug discovery through rapid identification and characterisation of therapeutic candidates. • Enhancing biopharmaceutical research by enabling detailed analysis of binding mechanisms critical to biologics development. • Facilitating translational research by bridging fundamental molecular interaction studies with clinical and therapeutic applications. This procurement will provide direct benefit to research scientists by: • Reducing manual intervention and experimental variability through automation and streamlined workflows. • Enhancing data quality with high-resolution detection and advanced signal processing for accurate kinetic profiling. • Please note: - The execution of this tender & contract will be solely dependent on grant funding being received, which is estimated to be confirmed in November 2025. • No award will be made, or orders issued until the grant funding has been confirmed. If grant funding is not secured, the market will be notified, and this procurement exercise will be stood down.

Renewal Options

Option to extend maintenance, software updates/development, the supply of consumables and ancillary items, beyond this period for a further period of up to 10 years or the end of useful life of the equipment.

Award Criteria

CPV Codes

• 38430000 - Detection and analysis apparatus
• 38432000 - Analysis apparatus

Indicators

• Renewals are available.

Other Information

** PREVIEW NOTICE, please check Find a Tender for full details. ** Amendment made to Tender response pack to enable suppliers to upload 2 x A4 pages instead of 1 x A4 pages for qualitative response questions.